By Thomas A. Buchholz, Eric A. Strom (auth.), David E. Wazer, Douglas W. Arthur, Frank A. Vicini (eds.)
Accelerated partial breast irradiation (APBI) is being quickly brought into the medical administration of early breast melanoma. APBI, in reality, contains a variety of varied innovations and methods that come with brachytherapy, intraoperative, and exterior beam strategies. there's at the moment no unmarried resource that describes those strategies and their medical implementation. this article is a concise guide designed to aid the clinician within the implementation of APBI. This features a evaluation of the rules that underlie APBI, a realistic and specific description of every procedure for APBI, a evaluation of present scientific result of APBI, and a overview of the prevalence and administration of therapy comparable complications.
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Additional resources for Accelerated Partial Breast Irradiation: Techniques and Clinical Implementation
Adv Surg 34:17–41 Silverstein MJ (2003) An argument against routine use of radiotherapy for ductal carcinoma in situ. Oncology (Huntingt) 17:1511–1533; discussion 1533–1514, 1539, 1542 passim Silverstein MJ, Lagios MD (2007) Should all patients undergoing breast conserving therapy for DCIS receive radiation therapy? No. One size does not ﬁt all: an argument against the routine use of radiation therapy for all patients with ductal carcinoma in situ of the breast who elect breast conservation. J Surg Oncol 95:605–609 Strnad V, Ott O, Potter R, et al.
In contemporary studies of patients managed in accordance with such modern practice, limited pathologic data are available that detail the extent of microscopic residual disease within the breast after “lumpectomy”—information that would be directly relevant for deﬁning the remaining target tissue. The contemporary studies that have addressed this question applied extensive microscopic evaluations of both mastectomy and quadrantectomy specimens and have consistently found that residual disease beyond the clinically evident primary tumor mass is most likely ductal carcinoma in situ (DCIS) (Faverly et al.
1992) Randomized clinical trial to assess the effectiveness of breast irradiation following lumpectomy and axillary dissection for node-negative breast cancer. J Natl Cancer Inst 84:683–689 Dewar JA, Haviland JS, Agrawal RK, et al. (2007) Hypofractionation for early breast cancer: ﬁrst results of the UK standardization of breast radiotherapy (START) trials. Proc Am Soc Clin Oncol 25(18):LBA518 Donovan E, Bleakley N, Denholm E, et al. (2007) Randomised trial of standard 2D radiotherapy (RT) versus intensity modulated radiotherapy (IMRT) in patients prescribed breast radiotherapy.
Accelerated Partial Breast Irradiation: Techniques and Clinical Implementation by Thomas A. Buchholz, Eric A. Strom (auth.), David E. Wazer, Douglas W. Arthur, Frank A. Vicini (eds.)